---
title: "Collision-induced dissociation: research glossary | Sable Peptides"
description: "Collision-induced dissociation (CID) is a fragmentation method in tandem mass spectrometry in which ions are accelerated and collided with neutral gas mole"
canonical: https://www.sablepeptides.co.uk/glossary/collision-induced-dissociation
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Collision-induced dissociation

Collision-induced dissociation (CID) is a fragmentation method in tandem mass spectrometry in which ions are accelerated and collided with neutral gas molecules, converting kinetic energy into internal energy that breaks chemical bonds. In peptides, CID mainly cleaves amide bonds to produce b and y fragment ions.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Collision-induced_dissociation)

## Related terms

-   [Mass spectrometry](/glossary/mass-spectrometry)
-   [Tandem mass spectrometry](/glossary/tandem-mass-spectrometry)

[Back to glossary A–Z](/glossary/terms)

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