---
title: "Capping: research glossary | Sable Peptides"
description: "Capping is a step in solid-phase peptide synthesis in which unreacted amines remaining after a coupling are acetylated, usually with acetic anhydride, so t"
canonical: https://www.sablepeptides.co.uk/glossary/capping
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Capping

Capping is a step in solid-phase peptide synthesis in which unreacted amines remaining after a coupling are acetylated, usually with acetic anhydride, so they cannot grow further. This converts potential deletion sequences into truncated peptides, which differ more from the target and are easier to remove during purification.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Peptide_synthesis)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Solid-phase peptide synthesis](/glossary/solid-phase-peptide-synthesis)

[Back to glossary A–Z](/glossary/terms)

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