---
title: "Aspartic acid: research glossary | Sable Peptides"
description: "Aspartic acid (three-letter code Asp, one-letter code D) is an acidic amino acid with a side-chain carboxyl group that is negatively charged at neutral pH."
canonical: https://www.sablepeptides.co.uk/glossary/aspartic-acid
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Aspartic acid

Aspartic acid (three-letter code Asp, one-letter code D) is an acidic amino acid with a side-chain carboxyl group that is negatively charged at neutral pH. Aspartic acid lowers a peptide's isoelectric point. In Fmoc synthesis it is prone to aspartimide formation, particularly in Asp-Gly and Asp-Ser sequences.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Aspartic_acid)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Amino acid](/glossary/amino-acid)
-   [Isoelectric point](/glossary/isoelectric-point)
-   [Aspartimide formation](/glossary/aspartimide-formation)
-   [One-letter code](/glossary/one-letter-code)

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