---
title: "Antagonist: research glossary | Sable Peptides"
description: "An antagonist is a substance that binds to a receptor without activating it, blocking or reducing the action of agonists. Competitive antagonists bind the"
canonical: https://www.sablepeptides.co.uk/glossary/antagonist
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Antagonist

An antagonist is a substance that binds to a receptor without activating it, blocking or reducing the action of agonists. Competitive antagonists bind the same site as the agonist, while non-competitive antagonists act at a different site. Peptide antagonists are used as tools to probe receptor function.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Receptor_antagonist)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Receptor](/glossary/receptor)
-   [Agonist](/glossary/agonist)

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