---
title: "Ammonium bicarbonate: research glossary | Sable Peptides"
description: "Ammonium bicarbonate (NH4HCO3) is a volatile buffer salt often used to dissolve acidic peptides and in sample preparation for mass spectrometry, because it"
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publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Ammonium bicarbonate

Ammonium bicarbonate (NH4HCO3) is a volatile buffer salt often used to dissolve acidic peptides and in sample preparation for mass spectrometry, because it decomposes to ammonia, carbon dioxide and water on drying. Solutions typically have a pH around 7.8, and it is removed by lyophilisation.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Ammonium_bicarbonate)

## Related terms

-   [Lyophilisation](/glossary/lyophilisation)
-   [Buffer](/glossary/buffer)
-   [Mass spectrometry](/glossary/mass-spectrometry)

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