---
title: "Acetic acid: research glossary | Sable Peptides"
description: "Acetic acid (CH3COOH) is a weak carboxylic acid used in peptide chemistry as a mild solvent for basic peptides, as a mobile phase modifier, and in counter-"
canonical: https://www.sablepeptides.co.uk/glossary/acetic-acid
publisher: Sable Peptides Limited (UK company 17488610)
note: Research use only. Not for human or veterinary use.
---

Glossary

# Acetic acid

Acetic acid (CH3COOH) is a weak carboxylic acid used in peptide chemistry as a mild solvent for basic peptides, as a mobile phase modifier, and in counter-ion exchange to produce acetate salts. Dilute acetic acid, such as 0.1% to 10%, can help dissolve peptides that are poorly soluble in neutral water.

Source: [en.wikipedia.org](https://en.wikipedia.org/wiki/Acetic_acid)

## Related terms

-   [Peptide](/glossary/peptide)
-   [Counter-ion](/glossary/counter-ion)
-   [Mobile phase](/glossary/mobile-phase)

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